Methylglyoxal (MG) Competitive ELISA

Methylglyoxal (MG) Competitive ELISA
  • Rapid detection and quantitation of MG-H1 (methyl-glyoxal-hydro-imidazolone) protein adducts
  • Provides sufficient reagents to perform up to 96 assays, including standard curve and unknown protein samples

 

Frequently Asked Questions about this product

General FAQs about Oxidative Stress

Email To BuyerPrint this PageCopy Link
Ordering

Please contact your distributor for pricing.

OxiSelect™ Methylglyoxal (MG) Competitive ELISA Kit
Catalog Number
STA-811
Size
96 assays
Detection
Colorimetric
Manual/Data Sheet Download
SDS Download
Price
$755.00
OxiSelect™ Methylglyoxal (MG) Competitive ELISA Kit
Catalog Number
STA-811-5
Size
5 x 96 assays
Detection
Colorimetric
Manual/Data Sheet Download
SDS Download
Price
$3,250.00
Product Details

The OxiSelect™ Methylglyoxal (MG) ELISA Kit is an enzyme immunoassay developed for rapid detection and quantitation of MG-H1 (methyl-glyoxal-hydro-imidazolone) protein adducts.  The quantity of MG adduct in protein samples is determined by comparing its absorbance with that of a known MG-BSA standard curve.  Each kit provides sufficient reagents to perform up to 96 assays, including standard curve and unknown protein samples.

Recent Product Citations
  1. Nakamura, T. et al. (2023). Continuous low serum levels of advanced glycation end products and low risk of cardiovascular disease in patients with poorly controlled type 2 diabetes. Cardiovasc Diabetol. 22(1):147. doi: 10.1186/s12933-023-01882-9.
  2. Al-Robaiy, S. et al. (2022). RAGE-Dependent Effect of Exogenous Methylglyoxal Intake on Lung Biomechanics in Mice. Nutrients. 15(1):23. doi: 10.3390/nu15010023.
  3. Kim, H.J. et al. (2022). Vitamin A aldehyde-taurine adducts function in photoreceptor cells. Redox Biol. doi: 10.1016/j.redox.2022.102386.
  4. Yang, S.E. et al. (2022). Insulin sensitizer and antihyperlipidemic effects of Cajanus cajan (L.) millsp. root in methylglyoxal-induced diabetic rats. Chin J Physiol. 65(3):125-135. doi: 10.4103/cjp.cjp_88_21.
  5. Tisi, A. et al. (2022). Antioxidant Properties of Cerium Oxide Nanoparticles Prevent Retinal Neovascular Alterations In Vitro and In Vivo. Antioxidants. 11(6):1133. doi: 10.3390/antiox11061133.
  6. Oliveira, A.L. et al. (2022). Enhanced RAGE Expression and Excess Reactive-Oxygen Species Production Mediates Rho Kinase-Dependent Detrusor Overactivity After Methylglyoxal Exposure. Front Physiol. doi: 10.3389/fphys.2022.860342.
  7. Maciejczyk, M. et al. (2022). Oxidation, Glycation, and Carbamylation of Salivary Biomolecules in Healthy Children, Adults, and the Elderly: Can Saliva Be Used in the Assessment of Aging? J Inflamm Res. 15:2051-2073. doi: 10.2147/JIR.S356029.
  8. Santini, S.J. et al. (2022). Copper-catalyzed dicarbonyl stress in NAFLD mice: protective effects of Oleuropein treatment on liver damage. Nutr Metab (Lond). 19(1):9. doi: 10.1186/s12986-022-00641-z.
  9. Krisanits, B.A. et al. (2022). Non-enzymatic glycoxidation linked with nutrition enhances the tumorigenic capacity of prostate cancer epithelia through AGE mediated activation of RAGE in cancer associated fibroblasts. Transl Oncol. 17:101350. doi: 10.1016/j.tranon.2022.101350.
  10. Kim, M. et al. (2021). Anti-glycation effect and renal protective activity of Colpomenia sinuosa extracts against advanced glycation end-products (AGEs). J. Mar. Biosci. Biotechnol. 13(2):94-103. doi: 10.15433/ksmb.2021.13.2.094.
  11. Medeiros, M.L. et al. (2021). Methylglyoxal Exacerbates Lipopolysaccharide-Induced Acute Lung Injury via RAGE-Induced ROS Generation: Protective Effects of Metformin. J Inflamm Res. 14:6477-6489. doi: 10.2147/JIR.S337115.
  12. Pantner, Y. et al. (2021). DJ-1 attenuates the glycation of mitochondrial complex I and complex III in the post-ischemic heart. Sci Rep. 11(1):19408. doi: 10.1038/s41598-021-98722-1.
  13. Oliveira, A.L. et al. (2021). Metformin abrogates the voiding dysfunction induced by prolonged methylglyoxal intake. Eur J Pharmacol. 910:174502. doi: 10.1016/j.ejphar.2021.174502.
  14. Kim, M. et al. (2021). Ishige okamurae Ameliorates Methylglyoxal-Induced Nephrotoxicity via Reducing Oxidative Stress, RAGE Protein Expression, and Modulating MAPK, Nrf2/ARE Signaling Pathway in Mouse Glomerular Mesangial Cells. Foods. 10(9):2000. doi: 10.3390/foods10092000.
  15. Ragno, V.M. et al. (2021). Morphometric, metabolic, and inflammatory markers across a cohort of client-owned horses and ponies on the insulin dysregulation spectrum. J Equine Vet Sci. doi: 10.1016/j.jevs.2021.103715.
  16. Suh, K.S. et al. (2021). Protective effects of sciadopitysin against methylglyoxal-induced degeneration in neuronal SK-N-MC cells. J Appl Toxicol. doi: 10.1002/jat.4211.
  17. Gutierrez-Mariscal, F.M. et al. (2020). Reduction in Circulating Advanced Glycation End Products by Mediterranean Diet is Associated with Increased Likelihood of type 2 Diabetes Remission in Patients with Coronary Heart Disease: From the Cordioprev Study. Mol Nutr Food Res. doi: 10.1002/mnfr.201901290.
  18. Li, J. et al. (2020). Renal protective effects of empagliflozin via inhibition of EMT and aberrant glycolysis in proximal tubules. JCI Insight. pii: 129034. doi: 10.1172/jci.insight.129034.
  19. Piuri, G. et al. (2020). Methylglyoxal, Glycated Albumin, PAF, and TNF-α: Possible Inflammatory and Metabolic Biomarkers for Management of Gestational Diabetes. Nutrients. 12:479. doi: 10.3390/nu12020479.
  20. Shimizu, Y. et al. (2020). Role of DJ‐1 in Modulating Glycative Stress in Heart Failure. J Am Heart Assoc. 9(4). doi: 10.1161/jaha.119.014691.
  21. de la Cruz-Ares, S. et al. (2020). Endothelial Dysfunction and Advanced Glycation End Products in Patients with Newly Diagnosed Versus Established Diabetes: From the CORDIOPREV Study. Nutrients. 12(1). pii: E238. doi: 10.3390/nu12010238.
  22. Liu, C. et al. (2020). Inhibition of thioredoxin 2 by intracellular methylglyoxal accumulation leads to mitochondrial dysfunction and apoptosis in INS-1 cells. Endocrine. doi: 10.1007/s12020-020-02191-x.
  23. Egawa, T. et al. (2019). The Protective Effect of Brazilian Propolis against Glycation Stress in Mouse Skeletal Muscle. Foods. 8(10). pii: E439. doi: 10.3390/foods8100439.
  24. Do, M.H. et al. (2019). Schizonepeta tenuifolia reduces methylglyoxal-induced cytotoxicity and oxidative stress in mesangial cells. J Funct Foods. doi: 10.1016/j.jff.2019.103531.
  25. Nakamura, T. et al. (2019). Poorly controlled type 2 diabetes with no progression of diabetes-related complications and low levels of advanced glycation end products: A Case report. Medicine (Baltimore). 98(30):e16573. doi: 10.1097/MD.0000000000016573.
  26. Griggs, R.B. et al. (2019). Methylglyoxal and a spinal TRPA1-AC1-Epac cascade facilitate pain in the db/db mouse model of type 2 diabetes. Neurobiol Dis. 127:76-86. doi: 10.1016/j.nbd.2019.02.019.
  27. Shamsaldeen, Y.A. et al. (2019). Dysfunction in nitric oxide synthesis in streptozotocin treated rat aorta and role of methylglyoxal. Eur J Pharmacol. 842:321-328. doi: 10.1016/j.ejphar.2018.10.056.
  28. Simón, L. et al. (2018). Olive oil addition to the high-fat diet reduces methylglyoxal (MG-H1) levels increased in hypercholesterolemic rabbits. Mediterranean Journal of Nutrition and Metabolism. doi: 10.3233/mnm-180229.
  29. Thompson, K. et al. (2018). Advanced glycation end (AGE) product modification of laminin downregulates Kir4.1 in retinal Müller cells. PLoS One. 13(2):e0193280. doi: 10.1371/journal.pone.0193280.
  30. Suh, K.S. et al. (2018). Cytoprotective effects of xanthohumol against methylglyoxal-induced cytotoxicity in MC3T3-E1 osteoblastic cells. J Appl Toxicol. 38:180–192.