SARS-CoV2 Assays

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a novel form of coronavirus. It was first identified in three people related to the cluster of acute respiratory illness cases in Wuhan, China. SARS-CoV-2 can have effects on the sinuses, nose, and throat (upper respiratory tract) as well as the lungs and windpipe (lower respiratory tract).  The organ most affected by this virus is the lungs: SARS-CoV-2 enters host cells by binding to the enzyme angiotensin-converting enzyme 2 (ACE2), which is abundant in type II alveolar cells located in the lungs.  The virus binds to and enters human cells by using its surface spike glycoprotein (spike protein) to bind ACE2 on the host cell surface.  The protein makeup of SARS-CoV-2 includes membrane glycoprotein (M), envelope protein (E), spike protein (S), and the nucleocapsid protein (N).

All assays are for research use only; they are not to be used for any clinical, in vitro or in vivo human or veterinary diagnostic purposes.