Pantropic Retroviral Expression System, Universal

  • Achieve average titer of 10^7 infectious units/mL with transient transfection
  • Produce VSVG-pseudotyped pantropic retrovirus which will readily infect cells of nearly any species
  • Cloning capacity of pMXs-Neo expression vector = 3.8 kb
  • Cloning capacity of pMXs-Puro expression vector = 4.4 kb

 

NOTE: Platinum Retroviral Expression Systems are available for sale to academic, government and non-profit research laboratories. All other purchasers require a commercial license for all fields including research use. Please contact our Business Development department for license information.

 

Frequently Asked Questions about this product

General FAQs about Viral Gene Delivery

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Platinum Retroviral Expression System, Pantropic
Catalog Number
VPK-302
Size
1 kit
Detection
N/A
Manual/Data Sheet Download
SDS Download
Map Download
Sequence Download
Price
$1,040.00
Product Details

Retroviral vectors are useful for delivering genes of interest into a target cells where integration into the genome is desired. However, traditional retroviral expression technologies result in low viral titers, making gene expression studies challenging.

Platinum Retroviral Expression Systems incorporate superior packaging cell lines and vector technologies to produce high-titer virus with a single plasmid transfection. This system includes our exclusive Platinum-GP cell line which contains the gag and pol genes required for viral packaging. Simply clone your gene of interest into the vector provided and co-transfect into the packaging cells with the included VSVG plasmid.

Recent Product Citations
  1. Saito, Y. et al. (2015). Enhancement of spontaneous activity by HCN4 overexpression in mouse embryonic stem cell-derived cardiomyocytes-A possible biological pacemaker. PLoS One.  10:e0138193.
  2. Yamaguchi, J. et al. (2015). Inflammation and hypoxia linked to renal injury by CCAAT/enhancer-binding protein δ. Kidney Int. doi: 10.1038/ki.2015.21.
  3. Wang, N. et al. (2013). Lacritin Rescues Stressed Epithelia via Rapid Forkhead Box O3 (FOXO3)-associated Autophagy That Restores Metabolism. J. Biol. Chem. 288:18146-18161 (#VPK-302).
  4. Tanaka, T. et al. (2012). Anthracycline Inhibits Recruitment of Hypoxia-inducible Transcription Factors and Suppresses Tumor Cell Migration and Cardiac Angiogenic Response in the Host. J. Biol. Chem. 287: 34866-34882 (#VPK-302).