Successful gene expression studies using AAV depend on high transduction efficiencies into host cells. Infection rates appear to be highest in S-phase cells, which can account for a very small fraction of a cell population.
Our ViraDuctin™ AAV Transduction Reagent can significantly increase the transduction efficiency of AAV vectors in both dividing and non-dividing cells. Transduction increases are greatest in non-dividing cells, but even cells in S-phase can show a noticeable increase in transduction efficiencies.